邢成芬
职称:教授,博士生导师
xingc@hebut.edu.cn
教育背景:
2008-09至2011-07,中国科学院研究生院,博士
2005-09至2008-06,山东师范大学(中科院化学所联合培养),硕士
2001-09至2005-07,山东师范大学,学士
工作履历:
2019-09至今,河北工业大学,生命科学与健康工程学院,教授
2013-09至2019-09,河北工业大学,理学院,教授
学术兼职:
《ACS Applied Bio Materials》编委、《Chinese Chemical Letters》青年编委。
学术任职:
河北省分子生物物理重点实验室副主任
研究领域与承担项目:
研究领域:
刺激响应高分子构建、细胞化学通讯调控
基金和项目:
1 国家重点研发项目,2023-2026,主持
2国家重点研发计划,2023-2028,主持
3 国家自然科学基金,面上项目,2021-2024,主持
4 国家自然科学基金面上项目,2018-2021,主持
5 河北省青年拔尖人才项目,2019-2024,主持
6 河北省自然科学基金生物医药联合基金重点项目,2020-2023,主持
7 河北省自然科学基金杰出青年基金, 2017-2019,主持
奖励与荣誉:
1. “长江学者奖励计划”青年学者
2. 河北省重点培育创新团队(团队负责人)
3. 河北省政府特殊津贴专家称号
4. 河北省“百人计划”特聘专家称号
5. 劳模和工匠人才创新工作室
6. 天津市创新人才推进计划青年科技优秀人才
7. 天津市五一劳动奖章
代表性著作:
[1] Rang Sun, Xinyu Jin, Yuying Bao, Zhanshuo Cao, Dong Gao, Ran Zhang, Liang Qiu, Hongbo Yuan*, Chengfen Xing*, Microenvironment with NlR-Controlled ROS and Mechanical Tensions for Manipulating Cell Activities in Wound Healing, Nano Letters, 2024, (SCI一区, IF2023=10.8)
[2] Ning Li, Chen Li, Boying Li, Chaoqun Li, Qi Zhao, Zhongming Huang, Yue Shu, Xiongwei Qu, Baiqi Wang, Shengliang Li*, Chengfen Xing*; Dual Activation of Calcium Channels Using Near-Infrared Responsive Conjugated Oligomer Nanoparticles for Precise Regulation of Blood Glucose Homeostasis, Nano Letters, 2023, 23(22): 10608-10616 (SCI一区, IF2023=10.8)
[3] Boying Li, Yiying Wang, Dong Gao, Shuxi Ren, Li Li, Ning Li, Hailong An, Tiantian Zhu, Yakun Yang, Hailin Zhang*, and Chengfen Xing*, Photothermal Modulation of Depression-Related Ion Channel Function through Conjugated Polymer Nanoparticles, Advanced Functional Materials, 2021,31(19): 202010757 (SCI一区, IF2023=19.0) ( 本人标注: 共同通讯作者)
[4] Liang Qiu, Haoran Zhang, Thomas Bick, Johannes Martin, Petra Wendler, Alexander Böker, Ulrich Glebe*, and Chengfen Xing*, Construction of Highly Ordered Glyco-Inside Nano-Assemblies through RAFT Dispersion Polymerization of Galactose-Decorated Monomer, Angewandte Chemie International Edition, 2021, 60(20): 11098-11103 (SCI一区, IF2023=16.6) ( 本人标注: 共同通讯作者)
[5] Hao Geng, Yuchen Pan, Ran Zhang, Dong Gao, Zijuan Wang, Boying Li, Ning Li, Dongsheng Guo*, and Chengfen Xing*; Binding to Amyloid-β Protein by Photothermal Blood-Brain Barrier-Penetrating Nanoparticles for Inhibition and Disaggregation of Fibrillation, Advanced Functional Materials, 2021, 31(41): 202102953 (SCI一区, IF2023=19.0) ( 本人标注: 共同通讯作者)
[6] Hongbo Yuan, Yong Zhan, Alan E. Rowan, Chengfen Xing*, and H. J. Kouwer Paul*, Biomimetic Networks with Enhanced Photodynamic Antimicrobial Activity from Conjugated Polythiophene/Polyisocyanide Hybrid Hydrogels, Angewandte Chemie International Edition, 2020,59(7): 2720-2724 (SCI一区, IF2023=16.6) ( 本人标注: 共同通讯作者)
[7] Zijuan Wang, Shuyi Qu, Dong Gao, Qi Shao, Chenyao Nie, and Chengfen Xing*, A Strategy of On-Demand Immune Activation for Antifungal Treatment Using Near-Infrared Responsive Conjugated Polymer Nanoparticles, Nano Letters, 2022, 23(1): 326-335 (SCI一区, IF2023=10.8) (本人标注: 共同通讯作者 )
[8] Boying Li, Shuxi Ren, Dong Gao, Ning Li, Manman Wu, Hongbo Yuan, Mei Zhou, and Chengfen Xing*, Photothermal Conjugated Polymer Nanoparticles for Suppressing Breast Tumor Growth by Regulating TRPA1 Ion Channels, Advanced Healthcare Materials, 2022, 11(8): 2102506 (SCI一区, IF2023=10.0) (本人标注: 唯一通讯作者)
[9] Ning Li, Yijian Gao, Boying Li, Dong Gao, Hao Geng, Shengliang Li, and Chengfen Xing*,Remote Manipulation of ROS-Sensitive Calcium Channel Using Near-Infrared-Responsive Conjugated Oligomer Nanoparticles for Enhanced Tumor Therapy In Vivo, Nano Letters, 2022, 22(13): 5427-5433 (SCI一区, IF2023=10.8) (本人标注: 共同通讯作者)
[10] Zijuan Wang, Dong Gao, Hao Geng, and Chengfen Xing*, Enhancing hydrogen production by photobiocatalysis through Rhodopseudomonas palustris coupled with conjugated polymers, Journal of Materials Chemistry A, 2021, 9(35): 19788-19795 (SCI一区, IF2023=11.9) (本人标注: 唯一通讯作者)
[11] Hongbo Yuan, Jialiang Xu, P. van Dam Eliane, Giubertoni Giulia, L. A. Rezus Yves, Hammink Roel, J. Bakker Huib, Yong Zhan, Rowan E. Alan, Chengfen Xing*, and Kouwer H. J. Paul*, Strategies To Increase the Thermal Stability of Truly Biomimetic Hydrogels: Combining Hydrophobicity and Directed Hydrogen Bonding, Macromolecules, 2017, 50(22): 9058-9065 (SCI一区, IF2023=5.5) ( 本人标注:共同通讯作者)
[12] Ran Chai, Chengfen Xing*, Junjie Qi, Yibing Fan, Hongbo Yuan, Ruimin Niu, Yong Zhan*, and Jialiang Xu , Water-Soluble Conjugated Polymers for the Detection and Inhibition of Protein Aggregation, Advanced Functional Materials, 2016, 26(48): 9026-9031 (SCI一区, IF2023=19.0) ( 本人标注:共同通讯作者)
[13] Hongbo Yuan, Junjie Qi, Chengfen Xing*, Hailong An, Ruimin Niu, Yong Zhan, Yibing Fan, Wenmin Yan, Ruihua Li, Bing Wang, and Shu Wang*, Graphene-Oxide-Conjugated Polymer Hybrid Materials for Calmodulin Sensing by Using FRET Strategy, Advanced Functional Materials, 2015, 25(28): 4412-4418 (SCI一区, IF2023=19.0) (本人标注: 共同通讯作者)
[14] Chengfen Xing, Libing Liu, Qiong Yang, Shu Wang*, and Guillermo C. Bazan*, Design guidelines for conjugated polymers with light-activated anticancer activity, Advanced Functional Materials, 2011, 21(21): 4058-4067 (SCI一区, IF2023=19.0) (本人标注: 唯一第一作者)
[15] Chengfen Xing, Libing Liu, Zhiqiang Shi, Yuliang Li, and Shu Wang, Synthesis of zwitterionic water-soluble oligofluorenes with good light-harvesting ability, Advanced Functional Materials, 2010, 20(13): 2175-2180 (SCI一区, IF2023=19.0) (本人标注: 唯一第一作者)
[16] Chengfen Xing, Qingling Xu, Hongwei Tang, Libing Liu, and Shu Wang, Conjugated Polymer/Porphyrin Complexes for Efficient Energy Transfer and Improving Light-Activated Antibacterial Activity, Journal of the American Chemical Society, 2009, 131(36): 13117-13124 (SCI一区, IF2023=15.0) (本人标注: 唯一第一作者)
专利申请与授权情况:
[1]一种具有抗菌和抗病毒功能的水溶性共轭聚合物及其制备与应用专利申请权转让, 专利, 技术转让,河北凯尔威生物技术有限公司, 650.0000万元, 2020-8-28 (科技成果转化)。
[2] 一种多功能空气净化膜及其制备方法专利技术出资, 专利, 技术转让, 河北凯尔威生物技术有限公司,
650.0000万元, 2020-8-28 (科技成果转化)。
[3] 吡咯并吡咯二酮类共轭寡聚物及基于其的纳米粒子以及它们的制备方法, 邢成芬; 吴曼曼; 高冬; 高梦诗,专利号:2019 1 1126229.9,授权日期: 2019-11-18。
[4] 一种基于共轭聚合物的近红外光响应的光热效应纳米粒子及其制备与应用, 邢成芬, 李博颖,高冬, 吴曼曼,专利号:2019 1 1126580.8,授权日期:2019-11-18。
[5] 一种基于螺旋聚乙腈多肽仿生矿化复合水凝胶的制备及其应用,邢成芬,袁宏博,曹展硕,高冬,展永,专利号:2021 1 0419997.4,授权日期:2021-04-19。
[6] 一种具有抗菌和抗病毒功能的水溶性共轭聚合物及其制备与应用,展永,邢成芬,高冬,齐俊杰,安海龙,专利号:2020 1 0541408.5,授权日期:2022-06-15。
[7] 两亲性共轭寡聚物及其制备及利用其自组装制备得到的载药纳米粒子,邢成芬,高梦诗,高冬,陈立权,专利号: 2020 1 1548533.5,授权日期:2020-12-24。
[8] 一种基于光热效应调控二氧化碳吸附的共轭高分子材料,邢成芬,李大伟,高冬,专利号:2019 1 0072129.6,授权日期:2019-01-25。
[9] 基于刺激响应共轭聚合物用于检测二氧化碳含量或转化的方法,邢成芬,袁宏博,展永,安海龙,齐俊杰,专利号:2015 1 0295086,授权日期:2015-06-02。
[10] 一种多功能空气净化膜及其制备方法,展永,邢成芬,齐俊杰,牛瑞民,安海龙,袁宏博,专利号: 2016 1 0628443.4,授权日期:2016-07-31。
[11] 一种高通量筛选光动力抗菌光敏剂的方法,邢成芬,牛瑞民,李瑞华,齐俊杰,展永,袁宏博,安海龙,专利号:2015 1 0320422.1,授权日期:2015-06-11。
[12] 一种基于氧化石墨烯和共轭聚合物复合材料的生物大分子构象变化检测方法,展永,邢成芬,袁宏博,安海龙,李瑞华,牛瑞民,专利号:2015 1 0118279.8,授权日期:2015-03-18。
[13]一种基于共轭聚合物的二氧化碳原位检测方法,邢成芬,范一冰,展永,齐俊杰,专利号:2016 1 1102075.6,授权日期:2016-12-05。
招生专业:
化学(学硕) 化学工程(专硕)